When interpreted by professionals, our initial results demonstrate useful findings and may be used downstream by law enforcement and public policy makers for impactful structural interventions to the opioid crisis. Although a large body of current research is focused on pathways for treatment of opioid use disorder and analyzing deaths per treatment capacity of substance use providers, these research areas are limited to the demand side of the opioid epidemic [40,41]. We believe that the findings and pattern analyses presented here, which place concentration on the supply side, might suggest a new direction to focus and will serve as a useful complement to current research conducted within the domain of addiction medicine. This section elaborates on the methodology used to identify opioid trading information in the anonymous market and forums. Specifically, we collected approximately 248,359 unique listings and 1,138,961 unique forum traces (ie, threads of posts) from 10 anonymous online marketplaces and 6 forums.
DrugHub Market
The government’s focus on expanding cancer treatment centers and facilitating access to modern therapeutics are fostering market development. The presence of international pharmaceutical companies and ongoing research collaborations further enhance treatment options. As the healthcare system continues to evolve, Sri Lanka is positioning itself as a key player in regional cancer management, with an emphasis on innovative therapies and patient-centric care models. Indonesia’s pancreatic and bile duct cancer drug market is anticipated to expand rapidly, driven by increasing disease awareness and a burgeoning healthcare sector. Government initiatives aimed at improving cancer screening and treatment infrastructure are pivotal. The rising prevalence of risk factors such as smoking and obesity contributes to higher cancer incidence.
📊 Market Stats & Reputation
- Challenges such as limited healthcare resources are being addressed through policy reforms and investments in diagnostic facilities.
- We maintain a zero-tolerance policy for prohibited items toensure marketplace safety and for the health of the darknet ecosystem.
- Select products, specify quantities, and provide encrypted shippinginformation using our secure order form.
- Once the item is received, the buyer finalizes the purchase by notifying the anonymous online marketplace to release the funds held in escrow (step 11) [8,9].
- The baseline model was applied directly to the labeled data (Table 3) and evaluated using 10-fold cross-validation.
- Additionally, DrugHub provides vendors with access to private mirrors, adding an extra layer of security against unauthorized access.
Emerging markets are showing promising potential due to improving healthcare infrastructure and heightened awareness. This analysis provides a comprehensive overview of the current market landscape, key regional trends, and the technological innovations shaping the future of pancreatic and bile duct cancer treatments across diverse geographic regions. Inspired by the work [36] investigating the supplier migration phenomenon between underground marketplaces, we also evaluated the migrant suppliers who, for the first time, began to trade in a new market, m’, after the closure of marketplace m.
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Once the item is received, the buyer finalizes the purchase by notifying the anonymous online marketplace to release the funds held in escrow (step 11) [8,9]. After that, an opioid buyer often leaves review comments under the product listing or discusses the purchasing experience in the forum (step 12). The Vietnamese market for pancreatic and bile duct cancer drugs is projected to grow steadily over the next five years, driven by increasing healthcare investments and rising awareness about early diagnosis. The expanding pharmaceutical sector and government initiatives to improve cancer care infrastructure are crucial factors. Additionally, the growing prevalence of these cancers among the aging population is expected to boost demand for advanced therapeutics. Market players are increasingly focusing on local collaborations and clinical research to enhance treatment options tailored to regional patient needs.
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First, we designed and implemented an anonymous marketplace data collection and analysis pipeline to gather and identify opioids data in 16 anonymous marketplaces and forums over a period of almost 9 years between 2011 and 2020. Second, we fine-tuned the semantic comparison model proposed by Yuan et al [19] for opioid jargon detection, which can recognize the opioid jargon as innocent-looking terms and the dedicated terms only used in the anonymous marketplaces and forums. In this way, we generated a rich underground marketplace opioid vocabulary of 311 opioid keywords with 13 categories.
🔢 Listings & Vendors
Thus, we identified 58 opioid jargon used in the anonymous marketplaces and forums (Table 2). Combining opioid jargon with known opioid product names [25-27], we generated an opioid keyword data set consisting of 311 opioid keywords with 13 categories. We manually validated all keywords and the corresponding categories to guarantee their correctness.
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Particularly, as shown in Table 8, the United States and the United Kingdom are always in the top 5 advertised origins among years. We compared our method with the state-of-the-art topic modeling method Machine Learning for Language Toolkit (MALLET) [30] and our model without transfer learning stage (baseline). In particular, MALLET is retrained and evaluated via 10-fold cross-validation. We also applied the MALLET topic modeling toolkit (package cc.mallet.topics MALLET’s class in JavaDoc API) on the same data set to predict the type of topic. The baseline model was applied directly to the labeled data (Table 3) and evaluated using 10-fold cross-validation. We used the metrics of precision and recall to compare the performance of different topic modeling methods.
Bangladesh Pancreatic And Bile Duct Cancer Market characteristics
In early 2025, the company broke ground on a $2 billion manufacturing facility project in Wilson. The drugmaker followed that up with a $2 billion deal in September for manufacturing space at Fujifilm Biotechnologies’ Holly Springs location. It also recently announced plans to build a second multibillion-dollar facility in Wilson. I am probably one of Smith Drug Company’s best advocates because of their customer service. There were multiple shortages on our shipments; Smith Drug Company was able to step in and get us what we needed in a timely fashion.
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A hurricane came through our area, our rep actually delivered our order in his vehicle when delivery trucks couldn’t get through. He made sure that all of his stores had what they needed to stay open and serve customers. Our merchandisers and pharmacy experts can maximize your success as a business owner. Whether its guidance on setting up the front end or information on new offerings and products, our customers regularly share feedback on what a difference our team has made to their store.
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HUB develops disruptive PDOs that accurately replicate human drug responses compared to animal models and cell lines, greatly increasing the value and impact of drug development programs. DrugHub Market is the most advances and security driven market on the darknettoday. With a proven team and billions of dollars in transactions DrugHubmarket can be used with the confidence that your data is fully protected. Violations of platform rules can result in a fine, account suspension andfund forfeiture. We maintain a zero-tolerance policy for prohibited items toensure marketplace safety and for the health of the darknet ecosystem. Stay informed about the latest darknet marketplaces, secure browsing practices, and privacy tools.
LOTTE Biologics Tightens Global Quality as Syracuse ADC Hub Ramps for 2026
Increasing awareness campaigns and government support for cancer management initiatives are key contributors. The expanding pharmaceutical sector and international partnerships are facilitating access to innovative therapies. Challenges such as limited healthcare resources are being addressed through policy reforms and investments in diagnostic facilities. The focus on expanding treatment options and clinical research is expected to accelerate market growth, making Pakistan an emerging hub for pancreatic and bile duct cancer therapeutics in the region. Sri Lanka’s pancreatic and bile duct cancer drug market is expected to grow steadily, supported by increased healthcare spending and improved diagnostic capabilities. Rising awareness about cancer symptoms and early detection programs are crucial factors.
From our measurement, we concluded that anonymous online marketplaces and forums provided easy-access platforms for global opioid supply. This paper seeks to complement current studies widening the understanding of opioid supply chains in underground marketplaces using comprehensive, large-scale, longitudinal anonymous marketplace and forum data. To this end, we propose a series of techniques to collect data; identify opioid jargon terms used in the anonymous marketplaces and forums; and profile the opioid commodities, suppliers, and transactions. Specifically, we first conducted a whole-site crawl of anonymous online marketplaces and forums to solicit data. Subsequently, we conducted a comprehensive, large-scale, longitudinal study to demystify opioid trading activities in anonymous markets and forums. In total, we collected 248,359 listings from 10 anonymous online marketplaces and 1,138,961 traces (ie, threads of posts) from 6 underground forums.
Former Sinaloa cartel kingpin Ismael ‘El Mayo’ Zambada set to plead guilty
Enhanced account security through mandatory 2FA implementation usingtime-based one-time passwords (TOTP), preventing unauthorized access even ifcredentials are compromised. Critical security announcements are posted on the marketplace homepage and this clearnet site. We will never announce emergency procedures through forums, Telegram, or other third-party channels. Primary support is provided through the marketplace ticketing system accessible after login. This ensures secure, encrypted communication with verification of staff identity.
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This is the only official marketplace URL—any other address claiming to be Drug Hub is a phishing attempt. In this way, we collected 7100 promotion posts and 6408 review posts from forum posts in total. Recovered from the scene were nearly five kilograms of high-grade marijuana or “Kush” valued at P5.86 million, and over 1.5 kilograms of shabu worth around P17.3 million.
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They usually come with anonymous forums for sellers and buyers to share information, promote their products, leave feedback, and share experiences about purchases. To understand how it works, we describe an opioid transaction’s operational steps on the anonymous online marketplaces and forums. We present a view about how such services operate and how different entities interact with each other (Figure 1).
Young People.
The opioid trader will also use an anonymous online forum (eg, The Hub Forum) to post promotional information to attract potential customers (step 3). Our study used opioid keywords and jargons to recognize listings and forum traces related to underground opioid trading activities. Our opioid jargon identification procedure implemented a modified semantic comparison model [19]. This model employed a neural network–based embedding technique to analyze the semantics of words in different corpora.
Find our official onion link and verified mirror here to access ourmarketplace for an unparalleled, private browsing experience. This finding is roughly in line with the observation of 57 opioid vendors’ origin in a marketplace named Cryptomarket during the period of October 2015 through April 2016, which was reported by Duxbury et al [6]. In addition, we did not observe big changes in the top opioid commodity origins from 2014 to 2020.
We offer our customers all the tools, products and services they need to thrive in a highly competitive environment. Each of our distribution centers is staffed with representatives who work with you personally for fast resolutions. Whether it’s IT support, or a question about an order, your call is answered by a real person in your region who will work with you until you have what you need. It’s no coincidence that our customer satisfaction is rated the highest in the industry. Withdrawals are processed securely with multiple verification steps toensure fund safety and prevent unauthorized access.
Those suppliers kept using the same IDs for years to gain reputation and familiarity from buyers. Co-occurrence of the same opioid suppliers across different anonymous marketplaces. The results provide insight into opioid trading in the anonymous markets and forums and may prove an effective mitigation data point for illuminating the opioid supply chain. Welcome to Drughub Market, the premierdarknet platform crafted by the esteemed drug hub White House Market team, operatingsecurely for over 2 years. As the number one market today, we pride ourselves onour advanced escrow protection androbust security systems, ensuring every transaction remains safe and secure. Monero (XMR) is the sole payment method,providing maximum privacy and anonymity for users navigating the dark web.Launched two years ago, Drughub Market has set the standard for reliability andsecurity.
Additionally, DrugHub provides vendors with access to private mirrors, adding an extra layer of security against unauthorized access. Note that data for 2020 only included data from January to March; price per gram is in US $. Each year, Frost & Sullivan presents this award to the company that has developed a product with innovative features and functionality that is gaining rapid acceptance in the market. The award recognizes the quality of the solution and the customer value enhancements it enables. M&A activities help companies expand capabilities, market reach, and competitive positioning.
Frost & Sullivan Best Practices Awards recognize companies in various regional and global markets for demonstrating outstanding achievement and superior performance in leadership, technological innovation, customer service, and strategic product development. Industry analysts compare market participants and measure performance through in-depth interviews, analyses, and extensive secondary research to identify best practices in the industry. HUB meticulously crafts its targeted marketing campaigns to highlight specific applications of organoid technology to accelerate and improve drug testing.
Its assets include Cleveland Clinic Abu Dhabi and Moorfields Eye Hospital Abu Dhabi, as well as initiatives like the Emirati Genome Program and Abu Dhabi BioBank. DrugHub Market is the #1 darknetmarketplace launched in August 2023 by the legendary team behind WhiteHouse Market. Now over 3 years strong, DrugHub boasts 100,000+ listings, over 500,000users, and more than 4,000 verifiedvendors. We are the premier platform for secure, private, Monero(XMR)-only transactions, with industry-leading security and uptime.
The platform is built with robust security features, including anti-DDOS and anti-phishing measures, making it one of the most secure marketplaces on the Tor network. Data set summary of marketplaces and forums that were collected for this study. If you value privacy and security in your darknet transactions, DrugHub Market is a strong contender. With its XMR-only policy, anti-DDOS protections, and secure vendor mirrors, DrugHub has solidified its position as a leading privacy-centric darknet marketplace. Established through the merger of G42 Healthcare and Mubadala Health, M42 is fast-becoming a major player in global healthcare. The company already employs more than 20,000 people, and operates over 480 facilities across 26 countries, integrating genomics, biobanks, digital health data and AI technologies to deliver predictive, personalized healthcare.
Build your drug empire from the ground up in the grungy west-coast city of Hyland Point. Contend against intensifying law enforcement and deadly cartel competitors to expand your empire and reach the peak of the underworld. With Philadelphia a long-established pharma hotspot and Pittsburgh an emerging one, Pennsylvania’s life sciences sector employs 100,000 workers across nearly 3,100 companies that have secured more than 10,700 new life sciences patents over the past five years. With its business-friendly environment and Texas Medical Center’s biomanufacturing project, TMC BioPort, the state proved an attractive investment location for other companies in 2025, too. Novartis plans to build two new radioligand therapy manufacturing facilities in Florida and Texas, and in October, the U.K.’s AstraZeneca opened an expanded manufacturing facility in Coppell to double the production of its high blood potassium treatment, Lokelma. We offer the most extensive assortment of products available, including access to specialty medications, OTC, HME, brand and generic pharmaceuticals.
In the above objective function, C+ is always larger than C−, which means that the penalty of misclassifying a positive instance is larger than that of a negative instance. In general, the correlation between the penalty factors and the number of samples is set as , where P and C are the sizes of Dp and Dc, respectively. As the leading publication for Filipinos in Dubai, we strive to deliver timely and accurate news, covering a wide range of topics that are relevant to our readers’ lives. From breaking news and current affairs to lifestyle, culture, business, and beyond, we aim to provide comprehensive coverage that reflects the interests and experiences of the Filipino diaspora.
As you can see DrugHub.link & DrugHub.su use the same IP address although it might seems suspicious that drughub.su would be seen using Cloudflare as of Today & DrugHub.link would be seen using an IP that was never updated between today and the November 25th 2024. Professionals based in North Yorkshire who work with people who use alcohol or other drugs can also book onto free training courses through Drink Drug Hub. DrugHub Market’s exclusive use of Monero and its advanced security features make it a top choice for darknet users. Its privacy-first approach ensures that users can transact with confidence, while the private vendor mirrors provide additional protection for vendors.
Our commitment to quality research and client success has established us as a trusted name in global market intelligence. Our team of seasoned analysts and researchers combines advanced methodologies, reliable data sources, and cutting-edge tools to produce detailed market reports, customized consulting solutions, and strategic recommendations. By identifying emerging trends, mapping growth opportunities, and evaluating competitive landscapes, we empower clients to navigate complex market dynamics with confidence. Produce a range of drugs to satisfy your customers, each one with it’s own unique production process. Discover special recipes to create new drug variants with special properties. He hung around with a rough crowd of Special Forces operatives in Fayetteville who drank heavily, took copious amounts of drugs and told graphic war stories in each others’ company while boasting about the numbers of people they had killed.
- To better understand the potential bundling relationship of opioid suppliers across different marketplaces, we calculated the Jaccard similarity coefficient between the suppliers in different marketplaces (Figure 6).
- The market for pancreatic and bile duct cancer drugs in Bangladesh is set to expand, driven by increasing disease prevalence and ongoing healthcare reforms.
- Another limitation is pointed out in the paper that multiple online suppliers might belong to the same vendor.
- When the buyer wants to check out and make a purchase using cryptocurrency (eg, Bitcoin), if the trader accepts payment through an anonymous online marketplace as an escrow, the buyer will place the listed amount of cryptocurrency in escrow (step 7).
- The opioid commodity with most listings across different marketplaces was #4 White Vietnamese Heroin, which can be found in the marketplaces Agora, Evolution, Hydra, and Pandora.
- We first conducted a whole-site crawl of anonymous online marketplaces and forums to solicit data.
- Danny has worked in technology communications for more than 20 years, and has been writing about developments the longevity sector since 2019.
Europe follows closely, driven by stringent regulatory standards, strong sustainability initiatives, and ongoing modernization across industrial and commercial sectors. The Asia-Pacific region is projected to register the fastest growth, propelled by rapid industrialization, expanding manufacturing capacity, urban development, and increasing uptake of cost-effective technologies across China, India, and Southeast Asian economies. Latin America offers emerging growth potential through infrastructure expansion and rising industrial activity, while the Middle East & Africa benefits from growing investments in energy, construction, and smart infrastructure projects. Collectively, regional diversification, supportive policy frameworks, and expanding end-use applications are generating substantial growth opportunities for the global Pancreatic And Bile Duct Cancer Drug Market. Always verify the complete onion URL character by character before entering any credentials. It exclusively supports XMR transactions, ensuring that all payments remain private and untraceable.
The opioid buyer (client) will also access the anonymous online market and create an account in each anonymous marketplace before they can find the listings of opioids (step 4). After perusing the items available on the anonymous online market (step 5), the buyer will add opioids to their shopping cart (step 6). When the buyer wants to check out and make a purchase using cryptocurrency (eg, Bitcoin), if the trader accepts payment through an anonymous online marketplace as an escrow, the buyer will place the listed amount of cryptocurrency in escrow (step 7). Otherwise, the buyer will pay the trader directly using cryptocurrency or any other payment method accepted by the trader (step 9) [7]. Note that the escrow mechanism is widely deployed in the anonymous online market because it helps to build trust and resolve disputes between sellers and buyers. When the purchase is made, the opioid trader ships the purchased item to the buyer (step 10).
Top priorities include expanding its strong quality culture across the organization to ensure a harmonized, global system, and nurturing the build-out of its new Bio Campus in Songdo, South Korea. If found guilty of these charges, Wilson faces a maximum penalty under federal law of life imprisonment, followed by a term of supervised release. The final sentence will be determined by a judge, taking into consideration applicable federal sentencing statutes and the Federal Sentencing Guidelines. It is important to note that indictments are formal accusations, and all individuals charged are presumed innocent until proven guilty in a court of law. The investigation into these alleged activities was a collaborative effort between the Federal Bureau of Investigation (FBI) and the Pennsylvania State Police. Assistant United States Attorney Scott Ford is overseeing the prosecution of this case.
